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Thursday 26 July 2012

True guilt is guilt at the obligation one owes to oneself to be oneself. False guilt is guilt felt at not being what other people feel one ought to be or assume that one is. Moderate feelings of guilt are beneficial because they encourage the individual to do the right thing

The Scottish psychologist R.D. Laing once said: True guilt is guilt at the obligation one owes to oneself to be oneself. False guilt is guilt felt at not being what other people feel one ought to be or assume that one is. Moderate feelings of guilt are beneficial because they encourage the individual to do the right thing. If nobody felt guilty about anything it would likely lead to a fearful world and it could even threaten the survival of the human species. There is also a more negative form of guilt which is excessive and harmful. This refers to a situation where the individual carries a sense of guilt around with them most of the time. The reasons for why the individual may become a victim of excessive guilt include: They have a poor self image. It can be a sign of mental health difficulties. Some people fall into negative thinking and this tends to include guilt. The individual has been a victim of physical or sexual abuse. Unhealthy relationships can leave people with feelings of guilt. Excessive stress. Alcohol or drug abuse.

Paper Passion, a scent from Geza Schoen for Wallpaper magazine, makes its wearers smell like freshly printed books

Paper Passion, a scent from Geza Schoen for Wallpaper* magazine, makes its wearers smell like freshly printed books. I suppose it can be alternated with "In the Library," a perfume that smells like old books.

Paper Passion fragrance by Geza Schoen, Gerhard Steidl, and Wallpaper* magazine, with packaging by Karl Lagerfeld and Steidl.

“The smell of a freshly printed book is the best smell in the world.” Karl Lagerfeld. 

It comes packaged with inside a hollow carved out of a book with "texts" by "Karl Lagerfeld, Günter Grass, Geza Schoen and Tony Chambers."

Tuesday 17 July 2012

ARNOLD SCHWARZENEGGER Back on the Hunt

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Arnold Schwarzenegger has accepted that his marriage is over ... and we know this because he was all over a 25-year-old chick at a party over the weekend.

Arnold was at Bagatelle restaurant in West Hollywood Friday night and lasered in on a 25-ish-year-old brunette.  The 64-year-old actor quickly made his move ... with his tongue.

But all good things -- like marriages -- must come to an end, and Arnold and the chick left separately.  On his way out, photogs asked him about Sage Stallone and eventually fired off a question about the chick ... but he wasn't in the mood to kiss and tell.

As for his divorce, we're told it's definitely going to happen.  But here's the twist.  After the story broke that Arnold fathered the maid's kid and Maria Shriver filed for divorce, he begged Maria to take him back, but she threw up roadblocks, demanding that he clean up his act.   On top of that, Maria changed her mind constantly -- one day wanting a divorce and the next wanting to reconcile.

Now we're told Arnold wants the divorce and Maria is the one who's tormented ... because she wants him back, but it's not going to happen.

Sources tell us both Arnold and Maria are now resigned to divorce, which should be official soon.

As for that 25-year-old chick ... we're told she's "kinda pretty, super skinny and hippie-like" -- rated a 7 by eyewitnesses -- which is 6 points higher than the maid.

Thursday 5 July 2012

Diabetes drug makes brain cells grow

The widely used diabetes drug metformin comes with a rather unexpected and alluring side effect: it encourages the growth of new neurons in the brain. The study reported in the July 6th issue of Cell Stem Cell, a Cell Press publication, also finds that those neural effects of the drug also make mice smarter. See Also: Health & Medicine Brain Tumor Stem Cells Nervous System Mind & Brain Brain Injury Intelligence Neuroscience Strange Science Reference Neural development Stem cell treatments Diabetes mellitus type 2 Embryonic stem cell The discovery is an important step toward therapies that aim to repair the brain not by introducing new stem cells but rather by spurring those that are already present into action, says the study's lead author Freda Miller of the University of Toronto-affiliated Hospital for Sick Children. The fact that it's a drug that is so widely used and so safe makes the news all that much better. Earlier work by Miller's team highlighted a pathway known as aPKC-CBP for its essential role in telling neural stem cells where and when to differentiate into mature neurons. As it happened, others had found before them that the same pathway is important for the metabolic effects of the drug metformin, but in liver cells. "We put two and two together," Miller says. If metformin activates the CBP pathway in the liver, they thought, maybe it could also do that in neural stem cells of the brain to encourage brain repair. The new evidence lends support to that promising idea in both mouse brains and human cells. Mice taking metformin not only showed an increase in the birth of new neurons, but they were also better able to learn the location of a hidden platform in a standard maze test of spatial learning. While it remains to be seen whether the very popular diabetes drug might already be serving as a brain booster for those who are now taking it, there are already some early hints that it may have cognitive benefits for people with Alzheimer's disease. It had been thought those improvements were the result of better diabetes control, Miller says, but it now appears that metformin may improve Alzheimer's symptoms by enhancing brain repair. Miller says they now hope to test whether metformin might help repair the brains of those who have suffered brain injury due to trauma or radiation therapies for cancer.

 

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